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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSK All Species: 40
Human Site: T365 Identified Species: 73.33
UniProt: P41240 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41240 NP_001120662.1 450 50704 T365 L R E K K F S T K S D V W S F
Chimpanzee Pan troglodytes XP_001138005 450 50665 T365 L R E K K F S T K S D V W S F
Rhesus Macaque Macaca mulatta XP_001101430 450 50702 T365 L R E K K F S T K S D V W S F
Dog Lupus familis XP_853247 465 51967 T380 L R E K K F S T K S D V W S F
Cat Felis silvestris
Mouse Mus musculus P41241 450 50595 T365 L R E K K F S T K S D V W S F
Rat Rattus norvegicus P32577 450 50728 T365 L R E K K F S T K S D V W S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P41239 450 50733 T365 L R E K K F S T K S D V W S F
Frog Xenopus laevis NP_001079062 450 50789 T365 L R E K L F S T K S D V W S F
Zebra Danio Brachydanio rerio NP_001071067 450 50999 T365 L R E K K F S T K S D V W S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731611 1052 113728 N969 L K N G R F S N K S D M W S F
Honey Bee Apis mellifera XP_393399 493 55500 N406 L K Q N K F S N K S D M W S F
Nematode Worm Caenorhab. elegans NP_001021778 539 60138 T457 L R H S Q F T T K S D V W S F
Sea Urchin Strong. purpuratus XP_795344 763 85563 F680 E A L R K K E F S S M S D V W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 99.7 95.4 N.A. 98.4 98.4 N.A. N.A. 93.3 83.7 85.7 N.A. 26.6 48.2 43.4 36.8
Protein Similarity: 100 98.4 100 96.1 N.A. 99.3 99.7 N.A. N.A. 95.3 90.4 93.1 N.A. 32.7 62.8 57.3 45.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 93.3 93.3 N.A. 60 66.6 73.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 93.3 100 N.A. 80 86.6 86.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 93 0 8 0 0 % D
% Glu: 8 0 70 0 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 93 0 8 0 0 0 0 0 0 85 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 16 0 70 77 8 0 0 93 0 0 0 0 0 0 % K
% Leu: 93 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 16 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 16 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 77 0 8 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 85 0 8 100 0 8 0 93 0 % S
% Thr: 0 0 0 0 0 0 8 77 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 77 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 93 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _